| ncRNA name | hsa-miR-181b |
| ncRNA Category | miRNA |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | human RB cell line HXO-RB44 |
| Methods | microarray, qRT-PCR, transfection |
| Expression pattern | up-regulated |
| Functional description | We identified a cluster of miRNAs that includes miR-181b, miR-125a-3p, miR-30c-2, miR-497 and miR-491-3p as hypoxia-regulated miRNAs (HRMs) in retinoblastoma cells, of which miR-181b was the most typically differentially expressed miRNA under hypoxic conditions. miR-181b inhibitor can suppress proliferation of retinoblastoma cells. |
| PubMed ID | 21373755 |
| Year | 2011 |
| Title | Microarray-based analysis: identification of hypoxia-regulated microRNAs in retinoblastoma cells. |
| Drug-related ncRNA | NO |
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